Mots-C Vial/ Kit

Single vial or 10-vial kit

MOTS-C Peptide – Research-Grade Mitochondrial Peptide

MOTS-C is a mitochondrial-derived peptide studied for its role in cellular energy regulation, metabolic signaling, and mitochondrial stress adaptation. Classified as a mitochondrial exercise-mimetic peptide, MOTS-C has gained significant attention in metabolic, aging, and endurance research models.

Royal Peptides supplies high-purity, third-party tested MOTS-C for laboratory research use only, with fast fulfillment from USA & Canada warehouses.

What Is MOTS-C?

MOTS-C (Mitochondrial Open Reading Frame of the 12S rRNA Type-C) is a 16-amino-acid peptide encoded by mitochondrial DNA rather than nuclear DNA — a rare and unique characteristic.

In preclinical research, MOTS-C has been observed to:

• Activate AMP-activated protein kinase (AMPK)
• Influence mitochondrial stress signaling
• Support metabolic flexibility
• Act as an exercise-mimetic signal in cellular models

Unlike traditional peptides synthesized from nuclear genes, MOTS-C is part of a small class of mitochondrial-encoded peptides (MDPs), placing it at the center of advanced mitochondrial biology research.

⚙️ Mechanism of Action (Research Overview)

In laboratory studies, MOTS-C has demonstrated the ability to:

• Translocate to the nucleus under metabolic stress
• Activate AMPK pathways, which regulate energy homeostasis
• Modulate glucose and fatty acid metabolism in cell models
• Support mitochondrial adaptation signaling

Researchers often categorize MOTS-C as a metabolic signaling peptide rather than a growth or structural peptide, making it especially relevant in:

• Metabolic research
• Endurance and fatigue studies
• Mitochondrial dysfunction models
• Aging-related cellular research

⚠️ Note: These effects are observed in preclinical and in-vitro research settings only.

MOTS-C in Scientific Research

MOTS-C is frequently referenced in studies exploring:

• Exercise mimetics
• Insulin signaling pathways
• AMPK activation
• Mitochondrial communication
• Age-associated metabolic decline

Because of its mitochondrial origin, MOTS-C is considered a next-generation research peptide, often studied alongside peptides such as SS-31, NAD⁺ precursors, and mitochondrial bioregulators.

Available MOTS-C Formats at Royal Peptides

Royal Peptides offers research-grade MOTS-C in multiple laboratory-preferred formats:

• MOTS-C 10mg
• MOTS-C 40mg
• Bulk & multi-vial kits available upon request

Each vial is:

• Lyophilized for stability
• Independently third-party tested
• Manufactured under controlled conditions
• Shipped discreetly and securely

Quality Assurance & Testing

Every MOTS-C batch supplied by Royal Peptides includes:

• ≥99% purity verification
• Third-party analytical testing
• Identity confirmation
• Contaminant screening

Certificates of Analysis (COAs) are available for qualified researchers upon request.

Shipping & Fulfillment

• USA fulfillment
• Canada fulfillment
• Same-day or next-business-day shipping on most orders
• Secure, discreet packaging

Royal Peptides specializes in fast, reliable fulfillment for both retail researchers and wholesale partners.

⚠️ Research Use Disclaimer

MOTS-C is sold strictly for laboratory research purposes only.

Not for human consumption, clinical use, or diagnostic application.

All buyers must be qualified researchers or purchasing on behalf of a research institution.

❓ Frequently Asked Questions (SEO Boost)

What is MOTS-C used for in research?

MOTS-C is studied for its role in mitochondrial signaling, metabolic regulation, AMPK activation, and exercise-mimetic pathways.

Is MOTS-C a mitochondrial peptide?

Yes. MOTS-C is encoded by mitochondrial DNA, making it part of the mitochondrial-derived peptide (MDP) class.

What makes MOTS-C unique?

Unlike most peptides, MOTS-C originates from the mitochondria and can signal between mitochondria and the nucleus, which is rare in cellular biology.

Is MOTS-C third-party tested?

Yes. All Royal Peptides MOTS-C products undergo independent third-party testing prior to release.

Why Researchers Choose Royal Peptides

• Research-only compliance
• High-purity peptide sourcing
• Transparent testing
• Fast North American shipping
• Trusted by labs and resellers

Royal Peptides is a premium research peptide supplier serving USA & Canada with consistent quality and reliability.

Additional information

Choose an option

40mg vial, 10mg vial, 10mg Kit (100mg), 30mg Kit (300mg), 40mg Kit (400mg)

Why Choose Royal Peptides?

Royal Peptides is the best place to buy peptides online. We are a trusted Research Chemicals vendor with formulations that meet industry standards and comply with quality regulations in Europe, USA, and Canada to ensure product safety and efficiency.

If you’re looking to buy research chemicals online, our one-stop shop offers a wide range of third-party tested, high-quality research chemicals made in the USA — including top-tier peptides, nootropics, amino acids, research oils, liquid research compounds, and more!

Our products are routinely and rigorously tested for purity, with Certificates of Analysis (COAs) verifiable through independent third-party laboratories.

Why Choose Royal Peptides?

Royal Peptides is the best place to buy peptides online. We are a trusted Research Chemicals vendor with formulations that meet industry standards and comply with quality regulations in Europe, USA, and Canada to ensure product safety and efficiency.

If you’re looking to buy research chemicals online, our one-stop shop offers a wide range of third-party tested, high-quality research chemicals made in the USA — including top-tier peptides, nootropics, amino acids, research oils, liquid research compounds, and more!

Our products are routinely and rigorously tested for purity, with Certificates of Analysis (COAs) verifiable through independent third-party laboratories.